Q:  What are the physiological benefits of altitude training?

A:  There are several beneficial changes affect the heart, lungs, circulatory system, and muscles:

  • Increase in blood flow to the lungs, promoting oxygen exchange
  • Increase of the permeability of the lungs to oxygen
  • Increase in the number of red blood cells able to carry oxygen
  • Increase in enzymes that facilitate release of oxygen from red blood cells into muscles
  • Increase in capillary density in muscles
  • Increase in the number of mitochondria (the energy-producing structures inside muscle cells)

Together, these changes represent a powerful combination of positive effects that can significantly improve your athletic performance.

Q:  What is EPO?  Isn't it banned?

A:  EPO (erythropoietin), a hormone naturally produced in the body, signals the bone marrow to begin the production of new red blood cells.  Everyone has
natural EPO in their body.  One of the main effects of altitude training is to stimulate the production of natural EPO.

Synthetic EPO is a drug developed for treatment of severe anemia, which may develop from cancer treatments or HIV infection.  As an athletic
performance booster, it is dangerous and illegal in all sports.  Doses of drug EPO are many times higher than natural amounts, and EPO doping has
injured and even killed otherwise healthy athletes due to stroke and heart attack resulting from overly-thick blood.  Altitude training stimulates your body's
natural production of EPO, rather than overwhelming your natural systems like "drug" EPO.

Q:  Will altitude training help my VO2 max go up?

A:   Quite probably, yes.  Your key to going faster is increasing the rate at which your body delivers oxygen to your muscles.  VO2 max, which measures
your maximum oxygen delivery rate, has been observed to increase 3-8%.  Scientists have also observed decreases of about 3% in the body's demand for
oxygen at a fixed running velocity (running efficiency).  This means you work less hard to go the same speed.  Even where VO2 max increases have not
been observed, other important performance measures such as time until exhaustion have increased substantially.   

Q:  Will my hematocrit rise?

A:   Quite probably, yes.  Hematocrit is a measure of the proportion of blood volume that is occupied by red blood cells.  The higher your hematocrit, the
more oxygen can be delivered per volume of blood.  As you generate new red blood cells, your hematocrit will rise.  In some cases, this can be partially
masked by a simultaneous increase in blood plasma volume.   A rise of 4-5 points is not unusual, but personal results cannot be predicted.  

Some sports place limits on hematocrit, e.g. 50%.  While doping with synthetic EPO can push you to 50% and beyond, it is unlikely that altitude training
could do so unless your pre-altitude baseline is exceptionally high.

Q:  Should I take any dietary supplements to help the process?

A:   Taking a B-Complex vitamin that includes Folate or Folic Acid is a good supplement to help your body build new red blood cells.  Iron is also
necessary, but supplemental iron should be added only with caution.  Your body probably has enough iron already, and excess iron cannot be excreted,
and can build up.  Men in particular should be very cautious about taking iron supplements, because it is easy for men to get iron overload.  A normal diet
with red meat and/or green leafy vegetables almost always provides enough iron for men.   Women, who are more prone to iron-deficiency anemia, might
consider additional iron, but only on the advice of a physician.

Q:  Should I have blood tests to monitor what is happening?

A:  You can, but probably isn’t necessary.  Simulated altitude training is very similar to going to high altitude.  People who go hiking or skiing in Colorado
don’t usually think about getting blood tests.  If you do, you will want to arrange both "before" and "after" tests, and look at hematocrit (red cell density) and
reticulocyte (new red blood cell) counts.

Q:  Can this help runner's anemia?

A:  For reasons that are not fully understood, long distance runners and other endurance athletes are prone to borderline anemia.  Various reasons have
been postulated, including destruction of blood cells from intense foot strike, reduced absorption of iron, and internal blood loss.  Whatever the cause, an
athlete with borderline anemia will not perform as well as an athlete with normal red blood cell density.  Normal hematocrit ranges from 40-50, and
borderline anemia may be considered to be the range 35-40.  Altitude training can help overcome runner's anemia.
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Physiology of Altitude Training